The global epidemic of obesity: are we becoming more sympathetic?
The global epidemic of obesity: are we becoming more sympathetic?
复制标题
全球肥胖流行病：我们是否变得更有同情心？
DOI：
10.1007/s11906-004-0076-7
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发表时间：
2004
影响因子：
5.6
通讯作者：
Davy,KevinP
中科院分区：
文献类型：
--
作者：
Davy,KevinP
The relationship between obesity and sympathetic nervous system (SNS) behavior has been controversial. Existing paradigms have been opposed in their views of the directional changes in SNS activity in obesity. In addition, limitations of previous approaches to assess SNS activity have produced inconsistent findings. However, the use of state-of-the-art neurochemical and neurophysiologic techniques has improved our current understanding of this issue. There is regional heterogeneity in the SNS activation associated with obesity, with the renal and skeletal muscle circulations, but not the heart, being targets for SNS activation. Abdominal visceral fat appears to be an important depot linking obesity and skeletal muscle SNS activation. The impact of this depot on SNS activity to the kidney or other regions is unknown. Future studies are needed to address this issue as well as the mechanisms and consequences of SNS activation in visceral obesity.
