HYPOXIC BRAIN-DAMAGE - CORTICAL LAMINAR NECROSIS AND DELAYED CHANGES IN WHITE-MATTER AT SEQUENTIAL MR-IMAGING
HYPOXIC BRAIN-DAMAGE - CORTICAL LAMINAR NECROSIS AND DELAYED CHANGES IN WHITE-MATTER AT SEQUENTIAL MR-IMAGING
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DOI：
10.1148/radiology.189.2.8210374
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发表时间：
1993-11-01
期刊：
影响因子：
19.7
通讯作者：
SUZUKI, M
中科院分区：
文献类型：
--
作者：
TAKAHASHI, S;HIGANO, S;SUZUKI, M
目的：报告缺氧性脑病的磁共振序列成像表现。材料和方法：对3名女性和3名男性进行重复的磁共振成像检查。结果：顶枕颞叶的分水岭受累比基底节、丘脑、海马体、桥脑和小脑的受累更频繁、更严重。急性期出现脑水肿。增强T1加权像在亚急性期早期显示皮质板层强化，平扫T1W像在亚急性期晚期显示大脑皮质特征性的板层高信号病变。这两个发现似乎都反映了皮质板层坏死的进展。慢性期可见皮质萎缩和延迟性进行性脑白质改变。结论：缺氧性脑损伤的MRI表现复杂而明显。可见皮质板层坏死、延迟性白质变性以及白质中铁沉积的增加。
PURPOSE: To report the findings of sequential magnetic resonance (MR) imaging in hypoxic encephalopathy.MATERIALS AND METHODS: Three women and three men underwent repeated MR imaging studies. Sequential changes in signal intensity and morphologic features of the brain were evaluated.RESULTS: Involvement of the watershed zones in the parietooccipitotemporal cortex was more frequent and more severe than that in the basal ganglia, thalami, hippocampus, pons, and cerebellum. Cerebral edema was seen in the acute stage. Enhanced T1-weighted images showed cortical laminar enhancement in the early subacute stage; unenhanced T1-weighted images revealed characteristic laminar hyperintense lesions of the cerebral cortex in the late subacute stage. Both of these findings seemed to reflect the progression of cortical laminar necrosis. In the chronic stage, cortical atrophy and delayed but progressive white matter changes were seen.CONCLUSION: Changes in MR imaging features of hypoxic brain damage are complex but distinct. Cortical laminar necrosis, delayed white matter degeneration, and, probably, increased iron deposition in the white matter can be delineated.