Tetherless thermobiochemically actuated microgrippers

Tetherless thermobiochemically actuated microgrippers
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DOI:
10.1073/pnas.0807698106
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发表时间:
2009-01-20
影响因子:
11.1
通讯作者:
Gracias, David H.
Gracias, David H.
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Leong, Timothy G.;Randall, Christina L.;Gracias, David H.

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我们展示了可大规模生产的无绳微夹具,可以在生物相关条件下通过温度和化学物质远程触发。微夹钳使用独立的驱动响应,无需在操作中使用外部系绳。即使在空间上分开,夹具也可以被集体驱动。我们使用微夹钳执行多种功能,例如拾取基板上的珠子以及从嵌入毛细管末端的组织中去除细胞(体外活检)。
We demonstrate mass-producible, tetherless microgrippers that can be remotely triggered by temperature and chemicals under biologically relevant conditions. The microgrippers use a self-contained actuation response, obviating the need for external tethers in operation. The grippers can be actuated en masse, even while spatially separated. We used the microgrippers to perform diverse functions, such as picking up a bead on a substrate and the removal of cells from tissue embedded at the end of a capillary (an in vitro biopsy).