Nondisruptive micropatterning of fluid membranes through selective vesicular adsorption and rupture by nanotopography.
Nondisruptive micropatterning of fluid membranes through selective vesicular adsorption and rupture by nanotopography.
复制标题
通过选择性囊泡吸附和纳米形貌破裂实现流体膜的非破坏性微图案化。
DOI：
10.1021/la8041082
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
S. Lee
中科院分区：
文献类型：
--
作者：
Sang‐Wook Lee;Yu;S. Lee
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We report on a nondisruptive method of patterning fluid membranes into micrometer-scale arrays through a selective vesicular rupture pathway by nanotopography. The site- and pathway-selective formation of supported lipid bilayers (SLBs) was achieved by different vesicular adsorption and rupture processes between nanocorrugated and nanosmooth topographies. The SLBs were first developed in the nanocorrugated region due to fast vesicular adsorption and then grew into the nanosmooth region through bilayer edge-induced vesicular rupture. Our topographic approach provides a viable scheme, yet unattainable in conventional ways, of actively controlling the position and the coverage of the SLBs on a variety of substrates without disrupting two-dimensional fluidity for highly integrated membrane devices.