Response of Sinorhizobium meliloti to Elevated Concentrations of Cadmium and Zinc
Response of Sinorhizobium meliloti to Elevated Concentrations of Cadmium and Zinc
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DOI：
10.1128/aem.02244-07
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发表时间：
2008-05
影响因子：
4.4
通讯作者：
S. Rossbach;Danielle J. Mai;E. L. Carter;L. Sauviac;D. Capela;C. Bruand;F. D. de Bruijn
中科院分区：
文献类型：
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作者：
S. Rossbach;Danielle J. Mai;E. L. Carter;L. Sauviac;D. Capela;C. Bruand;F. D. de Bruijn
摘要采用全基因组转录谱分析技术，对苜蓿中华根瘤菌1021在高浓度镉和锌胁迫下的差异表达基因进行了研究。对金属调节基因和编码推定金属外排泵基因插入突变株的金属敏感性进行了分析，揭示了SMc 04128编码的P型ATP酶在S.苜蓿对镉和锌胁迫的抗性。
ABSTRACT Whole-genome transcriptional profiling was used to identify genes in Sinorhizobium meliloti 1021 that are differentially expressed during exposure to elevated concentrations of cadmium and zinc. Mutant strains with insertions in metal-regulated genes and in genes encoding putative metal efflux pumps were analyzed for their metal sensitivities, revealing a crucial role for the SMc04128-encoded P-type ATPase in the defense of S. meliloti against cadmium and zinc stress.