Development of Electrospun Nanofibrous Filters for Controlling Coronavirus Aerosols
Development of Electrospun Nanofibrous Filters for Controlling Coronavirus Aerosols
复制标题
DOI：
10.1021/acs.estlett.1c00337
复制
发表时间：
2021-05-17
影响因子：
10.9
通讯作者：
Shen, Yun
中科院分区：
文献类型：
--
作者：
Shen, Hongchen;Zhou, Zhe;Shen, Yun
SARS-CoV-2的空气传播在COVID-19的传播中起着关键作用。为了保护公众健康，我们设计并制造了静电纺丝纳米纤维空气过滤器，有望应用于个人防护设备（PPE）和室内环境。由于超细纳米纤维（类似于300 nm），与外科口罩和布口罩相比，静电纺丝空气过滤器的孔径要小得多（几微米对几十到几百微米）。一种冠状病毒株作为SARS-CoV-2的替代物，用于产生用于过滤效率测试的气溶胶，与先前研究中用于气溶胶产生的其他试剂相比，该病毒株可以更好地代表SARS-CoV-2。静电纺丝空气过滤器表现出出色的性能，可捕获高达99.9%的冠状病毒气溶胶，优于许多商业口罩。此外，我们观察到，当两种气溶胶都是由同一系统产生时，与冠状病毒气溶胶相比，相同的静电纺丝空气过滤器或面罩去除NaCl气溶胶的效果相当或较低。我们的工作通过开发用于控制SARS-CoV-2空气传播的电纺纳米纤维空气过滤器，为推进空气过滤铺平了新的途径。
Airborne transmission of SARS-CoV-2 plays a critical role in spreading COVID-19. To protect public health, we designed and fabricated electrospun nanofibrous air filters that hold promise for applications in personal protective equipment (PPE) and the indoor environment. Due to ultrafine nanofibers (similar to 300 nm), the electrospun air filters had a much smaller pore size in comparison to the surgical mask and cloth masks (a couple of micrometers versus tens to hundreds of micrometers). A coronavirus strain served as a SARS-CoV-2 surrogate and was used to generate aerosols for filtration efficiency tests, which can better represent SARS-CoV-2 in comparison to other agents used for aerosol generation in previous studies. The electrospun air filters showed excellent performance by capturing up to 99.9% of coronavirus aerosols, which outperformed many commercial face masks. In addition, we observed that the same electrospun air filter or face mask removed NaCl aerosols equivalently or less effectively in comparison to the coronavirus aerosols when both aerosols were generated from the same system. Our work paves a new avenue for advancing air filtration by developing electrospun nanofibrous air filters for controlling SARS-CoV-2 airborne transmission.