Triterpenoids from the stems of Myricaria paniculata

Triterpenoids from the stems of Myricaria paniculata
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DOI:
10.1080/10286020410001721168
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发表时间:
2005-06-01
影响因子:
1.7
通讯作者:
Yu, DQ
Yu, DQ
中科院分区:
医学4区
文献类型:
--
作者:
Li, S;Dai, SJ;Yu, DQ

文献摘要

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从杨梅茎中分离到了两个新的五环三萜杨梅素A和B(1和2),同时分离到了杨梅素、28-羟基-14-taraxeren-3-one、外延蜜梨醇、β -谷甾醇、4-甲基柱头素-7-烯-3-醇、12-hentriacontanol和1-triacontanol 7个已知化合物。通过化学和光谱学方法确定了它们的结构。1和2对几种不同细胞系的细胞毒活性进行了评估。
Two new pentacyclic triterpenoids myricarin A and B (1 and 2) have been isolated from the stems of Myricaria paniculata , together with seven known compounds, myriconal, 28-hydroxy-14-taraxeren-3-one, epi -friedelanol, beta-sitosterol, 4-methyl stigmast-7-en-3-ol, 12-hentriacontanol and 1-triacontanol. Their structures have been established by chemical and spectroscopic methods. Cytotoxic activities of 1 and 2 have been evaluated against several different cell lines.