Cortex of the pedicle of the vertebral arch. Part II: microstructure
Cortex of the pedicle of the vertebral arch. Part II: microstructure
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DOI：
10.3171/spi-07/09/347
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发表时间：
2007-09-01
影响因子：
2.8
通讯作者：
Mclain, Robert F.
中科院分区：
文献类型：
--
作者：
Inceoglu, Serkan;Kilincer, Cumhur;Mclain, Robert F.
Object.虽然在人体脊柱椎弓根的大体解剖学已经进行了非常详细的研究，骨小梁和皮质结构的椎弓根的显微解剖学知识是有限的。了解椎弓根骨的力学性能和结构对于提高椎弓根螺钉置入质量至关重要。为了加强这种理解，作者检查了人类尸体腰椎。在这项研究中，作者获得了七个人的尸体，腰椎。将这些椎弓根样本的外侧和内侧皮质切片并包埋在聚甲基丙烯酸甲酯中。从每个标本中获得皮质的横截面切片，并在高分辨率光学显微镜的帮助下成像。评估骨方向，确定相对尺寸，并进行组织形态计量学研究。在每个人腰椎椎弓根的皮质有一个骨细胞结构，哈弗斯管主要在前后（纵向）方向。横截面上骨单位的组织结构是不均匀的。未观察到典型覆盖皮质骨结构的板层骨（如长骨），外侧皮质明显薄于内侧皮质（p < 0.05）。椎弓根周围的皮质骨不同于其他解剖区域的骨，如前椎体和股骨。椎弓根螺钉置入过程中椎弓根皮质的独特变形特征可能是由于骨向和缺乏板层鞘所致。
Object. Although the gross anatomy of the pedicle in the human spine has been investigated in great detail, knowledge of the microanatomy of trabecular and cortical structures of the pedicle is limited. An understanding of the mechanical properties and structure of the pedicle bone is essential for improving the quality of pedicle screw placement. To enhance this understanding, the authors examined human cadaveric lumbar vertebrae.Methods. In this study, the authors obtained seven human cadaveric,lumbar vertebrae. The lateral and medial cortices of these pedicle specimens were sectioned and embedded in polymethylmethacrylate. Cross-sectional slices of cortex were obtained from each specimen and imaged with the aid of a high-resolution light microscope. Assessments of osteonal orientation, determinations of relative dimensions, and histomorphometric studies were performed.Results. The cortex of the pedicle in each human lumbar vertebra had an osteonal structure with haversian canals laid down mainly in the anteroposterior (longitudinal) direction. The organization of osteons across the transverse cross-section was not homogeneous. The layer of lamellar bone that typically envelops cortical bone structures (such as in long bones) was not observed, and the lateral cortex was significantly thinner than the medial cortex (p < 0.05).Conclusions. The cortical bone surrounding the pedicle differed from bone in other anatomical regions such as the anterior vertebral body and femur. The osteonal orientation and lack of a lamellar sheath may account for the unique deformation characteristics of the pedicle cortex seen during pedicle screw placement.