Vancomycin-resistant enterococci in intensive care units - High frequency of stool carriage during a non-outbreak period
Vancomycin-resistant enterococci in intensive care units - High frequency of stool carriage during a non-outbreak period
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DOI：
10.1001/archinte.159.13.1467
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发表时间：
1999-07-12
影响因子：
--
通讯作者：
Samore, MH
中科院分区：
文献类型：
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作者：
Ostrowsky, BE;Venkataraman, L;Samore, MH
背景：我们旨在通过检查流行率、定植危险因素、获得频率和分子菌株类型，确定非疫情期间重症监护病房（icu）万古霉素耐药肠球菌（VRE）的流行病学关联。设计：采用前瞻性队列设计。本研究纳入了一家三级医院连续入住2个外科icu的患者。主要结局指标为VRE系列监测培养筛查结果。结果：入组的290例患者中，35例（12%）在入院时有VRE定植。这些患者中只有4例通过临床培养检测到VRE定植或感染。采用logistic回归分析，ICU入院时VRE定植与第二代和第三代头孢菌素相关(比值比[OR] = 6.0， P
Background: We aimed to define the epidemiological associations of vancomycin-resistant enterococci (VRE) in intensive care units (ICUs) during a non-outbreak period by examining prevalence, risk factors for colonization, frequency of acquisition, and molecular strain types.Design: A prospective cohort design was followed. Consecutive patient admissions to 2 surgical ICUs at a tertiary care hospital were enrolled. The main outcome measures were results of serial surveillance cultures screened for VRE.Results: Of 290 patients enrolled, 35 (12%) had colonization with VRE on admission. The VRE colonization or infection had been previously detected by clinical cultures in only 4 of these patients. Using logistic regression, VRE colonization at the time of ICU admission was associated with second- and third-generation cephalosporins (odds ratio [OR] = 6.0, P