Cumulative Patency of Contemporary Fistulas versus Grafts (2000-2010)
Cumulative Patency of Contemporary Fistulas versus Grafts (2000-2010)
复制标题
DOI：
10.2215/cjn.00730112
复制
发表时间：
2013-05-01
影响因子：
9.8
通讯作者：
Moist, Louise
中科院分区：
文献类型：
--
作者：
Lok, Charmaine E.;Sontrop, Jessica M.;Moist, Louise
背景和目标 瘘管和移植物的比较常常忽视瘘管的高原发失败率。本研究比较了瘘管和移植物的累积通畅率（从建立通路到永久失败的时间）。设计、设置、参与者和测量对来自两个中心（加拿大安大略省多伦多和伦敦，2000-2010 年）的 1140 名血液透析患者的血管通路进行了分析。使用 Kaplan-Meier 生存曲线和对数秩检验比较各组之间的累积通畅率。报告了相对于移植物的瘘管失败的风险比（HR）和95％置信区间（95％CI）。结果共有1012个（88.8％）瘘管和128个（11.2％）移植物。瘘管的初次失败率是移植物的两倍：40% 对比 19%（P
Background and objectives Comparisons of fistulas and grafts often overlook the high primary failure rate of fistulas. This study compared cumulative patency (time from access creation to permanent failure) of fistulas and grafts.Design, setting, participants, & measurements Vascular accesses of 1140 hemodialysis patients from two centers (Toronto and London, Ontario, Canada, 2000-2010) were analyzed. Cumulative patency was compared between groups using Kaplan-Meier survival curves and log-rank tests. Hazard ratios (HRs) for fistula failure relative to grafts and 95% confidence intervals (95% CIs) are reported.Results There were 1012(88.8%) fistulas and 128(11.2%) grafts. The primary failure rate was two times greater for fistulas than for grafts: 40% versus 19% (P