Uniformity in dynamic baroreflex regulation of left and right cardiac sympathetic nerve activities.
Uniformity in dynamic baroreflex regulation of left and right cardiac sympathetic nerve activities.
复制标题
左右心脏交感神经活动动态压力反射调节的一致性。
DOI：
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
K. Sunagawa
中科院分区：
文献类型：
--
作者：
T. Kawada;K. Uemura;K. Kashihara;Yintie Jin;Meihua Li;C. Zheng;M. Sugimachi;K. Sunagawa
心脏交感神经刺激在变时性和变力性作用中的功能偏侧性是众所周知的。在动态压力感受性反射激活过程中，左(LSNA)和右(RSNA)心交感神经活动是否表现为偏侧性仍有待确定。在9只麻醉、切断迷走神经和去主动脉神经的兔身上，我们随机扰动两个颈动脉窦区的颈动脉窦内压(CSP)，同时记录LSNA和RSNA。从CSP到LSNA和从CSP到RSNA的压力感受性神经弧传递函数呈现出导数特征，即LSNA和RSNA反应的幅度随着CSP扰动输入频率的增加而增大。在LSNA和RSNA反应中，0.03-0.3赫兹频率增益增加的平均斜率无差异(9.7+/-2.9对9.7+/-3.1分贝/十，平均+/-SD)。在0.01~1 Hz的频率范围内，LSNA和RSNA的幅值比和相位差分别接近1弧度和零弧度。此外，在CSP从40 mm Hg到160 mm Hg的逐步扰动过程中，LSNA和RSNA的关系呈直线(r(2)在0.969到0.999之间)。这些结果表明，就群集性轴突活动而言，LSNA和RSNA的动态和静态压力感受性反射调节没有偏侧性。
Functional laterality of cardiac sympathetic nerve stimulation in chronotropic and inotropic effects is well known. Whether left (LSNA) and right (RSNA) cardiac sympathetic nerve activities show laterality during dynamic baroreflex activation remains to be determined. In nine anesthetized, vagotomized, and aortic-denervated rabbits, we randomly perturbed intracarotid sinus pressure (CSP) in both carotid sinus regions while simultaneously recording LSNA and RSNA. The baroreflex neural arc transfer function from CSP to LSNA and from CSP to RSNA revealed derivative characteristics, i.e., the magnitude of LSNA and RSNA responses became greater as the input frequency of CSP perturbation increased. The average slope of increasing gain in the frequencies between 0.03 and 0.3 Hz showed no difference between LSNA and RSNA responses (9.7 +/- 2.9 vs. 9.7 +/- 3.1 dB/decade, means +/- SD). The amplitude ratio and phase difference between LSNA and RSNA approximated unity and zero radians, respectively, in the frequencies from 0.01 to 1 Hz. In addition, the LSNA-RSNA relationship during stepwise CSP perturbation from 40 to 160 mmHg showed a straight line (r(2) ranged from 0.969 to 0.999). These findings indicate no laterality in the dynamic as well as static baroreflex regulation of LSNA and RSNA as far as grouped axonal activity is concerned.
影响因子：
20.1
作者：
Michael C. Andresen;Diana L Kunze
通讯作者：
Michael C. Andresen;Diana L Kunze
单一尖峰序列之间的相互作用：对整个神经测量的影响。
DOI：
10.1152/ajpregu.1989.256.4.r997
发表时间：
1989
期刊：
The American journal of physiology
影响因子：
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作者：
Andresen,MC;Yang,M
通讯作者：
Yang,M