Effect of different pion stopping volumes on the radiation response of mouse small intestine.
Effect of different pion stopping volumes on the radiation response of mouse small intestine.
复制标题
不同π介子停止体积对小鼠小肠辐射反应的影响。
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
H. Fritz
中科院分区：
文献类型：
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作者：
K. Rao;H. Fritz
该放射生物学研究是基于小鼠小肠中隐窝细胞存活率的测量，当动物暴露于由瑞士核研究所的多通道Piotron产生的5 cm 3（点）、350 cm 3和3010 cm 3（后两个是点扫描）π介子停止体积时。所获得的实验数据表明，有一个减少的生物有效性时，π介子治疗体积被扩大，无论是在一个单一的曝光或在四个分数的π介子剂量提供。r.b.e.的值π束相对于200 kVp的X射线在这项研究中使用的不同的实验条件。生物学效应随π介子阻止体积增加而降低的现象可归因于以下两个因素：（1）当π介子阻止体积增加时，高l.e.t.梁的组成部分;（2）所用的生物测试系统可能对辐射剂量率敏感，在本研究中所用的π介子体积中，辐射剂量率的变化率约为20。
This radiobiological investigation was based on measurements of crypt cell survival in mouse small intestine when the animals were exposed to 5 cm3 (spot), 350 cm3 and 3010 cm3 (the latter two were spot scans) pion stopping volumes generated by the multi-channel Piotron of the Swiss Institute for Nuclear Research. The experimental data obtained indicate that there was a decrease in biological effectiveness when the pion treatment volume was enlarged, irrespective of whether the pion dose was delivered in a single exposure or in four fractions. The r.b.e. values for pion beams relative to 200 kVp X-rays for the different experimental conditions used in this study are presented. The phenomenon of decreasing biological effectiveness with increasing pion stopping volume may be attributed to the following two factors: (1) when the pion stopping volume is increased there is a corresponding dilution of the high l.e.t. component of the beam; (2) the biological test system used may be sensitive to radiation dose rate which varied by a ratio of about 20 for the pion volumes used in this study.
π介子分次剂量对正常组织的影响：第二部分。
DOI：
10.1016/0360-3016(80)90250-3
发表时间：
1980
期刊：
International journal of radiation oncology, biology, physics
影响因子：
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作者：
Peters,LJ;Withers,HR;Mason,KA;DiCello,JF
通讯作者：
DiCello,JF