SEX-DIFFERENCES IN SUBSITE INCIDENCE OF LARGE-BOWEL CANCER
SEX-DIFFERENCES IN SUBSITE INCIDENCE OF LARGE-BOWEL CANCER
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DOI：
10.1007/bf02553336
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发表时间：
1983-01-01
影响因子：
3.9
通讯作者：
ISBISTER, WH
中科院分区：
文献类型：
--
作者：
STEWART, RJ;STEWART, AW;ISBISTER, WH
一项对新西兰一家主要医院大肠癌患者的回顾显示，与男性相比，女性右侧结肠肿瘤过多。这些观察结果刺激了1972年至1975年（4678例患者）新西兰全国大肠癌登记数据的分析。使用世界人口数字计算每个地点的发病率并进行年龄标准化。研究结果证实，女性的右半结肠癌发病率较高，男性的直肠癌发病率较高，并显示出从升结肠到直肠的显著趋势。观察到的男性和女性之间的差异表明肿瘤病因的差异，在评估治疗方式和结果时应考虑到这一点。
A review of patients with large-bowel cancer at a major New Zealand hospital showed an excess of right-sided colonic tumors in females compared with males. These observations stimulated analysis of the National Cancer Registry registration data for large-bowel cancer for the whole of New Zealand in the years 1972 to 1975 (4678 patients). Rates for each site were calculated and age-standardized, using world population figures. The findings confirmed that females have a higher incidence of right-sided colonic cancer and males a higher incidence of rectal cancer and showed a significant trend in this direction from the ascending colon toward the rectum. The observed differences between males and females suggest differences in the etiology of the tumor and should be taken into account in assessing modalities and outcomes of treatment.