Relation of electrocardiographic left ventricular hypertrophy with and without T-wave changes to systemic blood pressure, body mass, and serum lipids and blood glucose levels in Japanese men.
Relation of electrocardiographic left ventricular hypertrophy with and without T-wave changes to systemic blood pressure, body mass, and serum lipids and blood glucose levels in Japanese men.
复制标题
日本男性心电图左心室肥厚伴或不伴 T 波变化与全身血压、体重、血脂和血糖水平的关系。
DOI：
10.1016/s0002-9149(97)00504-3
复制
发表时间：
1997
期刊：
影响因子：
--
通讯作者：
T. Kawamura
中科院分区：
文献类型：
--
作者：
Y. Ichihara;M. Sugino;R. Hattori;T. Anno;Y. Mizuno;M. Yokoi;T. Kondo;M. Hirai;T. Kawamura
左心室 (LV) 肥厚，尤其是伴有 ST-T 异常，被认为是众多冠状动脉危险因素之一。根据心电图检查结果，选择 749 名日本男性，即心电图正常、左室肥厚但无 ST-T 段异常、左室肥厚伴 T 波平坦、左室肥厚伴 T 波负值。比较这 4 个年龄匹配组的冠状动脉危险因素。 T波负向或平坦的左室肥厚组具有较大的体重指数（24.9 vs 22.9 kg/m2）、较高的平均全身血压（111 vs 95 mm Hg）、较大的左室质量（265 vs 157 g）、较高的血糖（110 vs 100 mg/dl）、较高的血清甘油三酯（148 vs 122 mg/dl）、较高的总胆固醇（206）与 198 mg/dl）相比，高密度脂蛋白胆固醇（47 vs 54 mg/dl）低于正常组或左心室肥厚但无 T 波改变的组。在这些危险因素中，即使经过体重指数或体重指数和血压调整后，血压和血糖仍然较高。心电图左心室肥厚伴有 T 波改变意味着日本男性患冠状动脉疾病的风险较高。
Left ventricular (LV) hypertrophy, especially combined with an abnormal ST-T, is considered 1 of many coronary risk factors. Seven hundred forty-nine Japanese men were selected according to their electrocardiographic findings, i.e., normal electrocardiogram, LV hypertrophy without an abnormal ST-T segment, LV hypertrophy with a flat T wave, and LV hypertrophy with a negative T wave. Coronary risk factors were compared among these 4 age-matched groups. Groups with LV hypertrophy with negative or flat T waves had larger body mass index (24.9 vs 22.9 kg/m2), higher mean systemic blood pressure (111 vs 95 mm Hg), larger LV mass (265 vs 157 g), higher blood glucose (110 vs 100 mg/dl), higher serum triglyceride (148 vs 122 mg/dl), higher total cholesterol (206 vs 198 mg/dl), and lower high-density lipoprotein cholesterol (47 vs 54 mg/dl) than the normal group or the group with LV hypertrophy without T-wave change. Among these risk factors, blood pressure and glucose remained higher even after the adjustment by body mass index or by body mass index and blood pressure. Electrocardiographic LV hypertrophy with a changed T wave signified higher risk of coronary artery disease in Japanese men.