The ubiquitin-proteasome 26s pathway in liver cell protein turnover: Effect of ethanol and drugs

The ubiquitin-proteasome 26s pathway in liver cell protein turnover: Effect of ethanol and drugs
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DOI:
10.1111/j.1530-0277.2001.tb02400.x
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发表时间:
2001-05-01
影响因子:
3.2
通讯作者:
Higashitsuji, H
Higashitsuji, H
中科院分区:
医学3区
文献类型:
--
作者:
French, SW;Mayer, RJ;Higashitsuji, H

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本文是2000年在日本横滨举行的ISBRA会议上的一个专题讨论会的记录。椅子是塞缪尔·W。法国和R。J. Mayer主要内容包括:(1)泛素-蛋白酶体26 s通路在肝细胞蛋白质周转中的作用:酒精和药物的影响。French和F. Bardag-Gorce;(2)CYP 2 E1磷酸化和降解途径在酶诱导中的作用,Magnus Ingelman-Sundberg;(3)蛋白酶体在实验性慢性酒精中毒中氧化蛋白的蛋白水解中的作用,Helen Rouach;(4)酒精、蛋白水解和肝癌,R. J. Mayer;(5)乙醇喂养对肝细胞中ATP-泛素-蛋白酶体途径的影响,F.(6)E. Neve;(7)Gankyrin,一种在肝癌中普遍过表达的癌蛋白,H.东津次
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Samuel W. French and R. J. Mayer. The presentations were (1) The ubiquitin-proteasome 26s pathway in liver cell protein turnover: Effect of alcohol and drugs, by Samuel W. French and F. Bardag-Gorce; (2) The role of CYP2E1 phosphorylation and degradation pathway in the induction of the enzyme, by Magnus Ingelman-Sundberg; (3) Role of proteasome in the proteolysis of oxidized proteins in experimental chronic alcoholism, by Helen Rouach; (4) Alcohol, proteolysis and liver cancer, by R. J. Mayer; (5) Effect of ethanol feeding on the ATP-ubiquitin-proteasome pathway in the liver cell, by F. Bardag-Gorce; (6) Novel mechanisms and targets for intracellular transport of CYP2E1, by E. Neve; and (7) Gankyrin, an oncoprotein commonly over expressed in hepatoma, by H. Higashitsuji.