Dynamic interfaces between cells and surfaces: Electroactive substrates that sequentially release and attach cells

Dynamic interfaces between cells and surfaces: Electroactive substrates that sequentially release and attach cells
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DOI:
10.1021/ja038265b
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发表时间:
2003-12-10
影响因子:
15
通讯作者:
Mrksich, M
Mrksich, M
中科院分区:
化学1区
文献类型:
--
作者:
Yeo, WS;Yousaf, MN;Mrksich, M

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展示了一种结合双动态特性的电活性衬底。单层被设计成在施加电位时首先释放固定的配体,从而释放贴壁细胞。随后,底物的电氧化导致配体的固定化和贴壁细胞的迁移。
An electroactive substrate that combines dual dynamic properties is demonstrated. A monolayer is patterned to first release an immobilized ligand, and therefore adherent cells, on application of an electrical potential. Subsequently, electrical oxidation of the substrate results in immobilization of ligands, and migration of adherent cells.