Free-running 4D whole-heart self-navigated golden angle MRI: Initial results
Free-running 4D whole-heart self-navigated golden angle MRI: Initial results
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DOI：
10.1002/mrm.25523
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发表时间：
2015-11-01
影响因子：
3.3
通讯作者：
Stuber, Matthias
中科院分区：
文献类型：
--
作者：
Coppo, Simone;Piccini, Davide;Stuber, Matthias
PurposeTo测试的假设，冠状动脉解剖和心室功能可以同时使用一个单一的四维（4D）acquisition.MethodsA自由运行的4D全心脏自我导航采集纳入一个黄金角径向轨迹实施和测试在体内9个健康的成年人受试者。提取具有采集窗口宽度和位置回顾性选择的冠状动脉磁共振血管造影（MRA）数据集，并与基线自导航心电图（ECG）触发的冠状动脉MRA进行定量比较。从4D数据集，左心室收缩末期，舒张末期容积（ESV和EDV）和射血分数（EF）进行计算，并与从传统的2D电影images.ResultsThe 4D数据集获得的值进行比较，使动态评估的全心脏各向同性空间分辨率为1.15毫米（3）。冠状动脉图像质量与ECG触发的基线扫描非常相似，尽管存在一些SNR损失。4D和2D电影成像之间的一个很好的协议被发现EDV，ESV，和EF.ConclusionThe的假设，即冠状动脉解剖结构和心室功能，可以同时评估在体内已被测试阳性。回顾性和灵活的采集窗口选择允许最佳地可视化每个冠状动脉段在其各自的静止时间点。Magn Reson Med 74：1306-1316，2015. (c)2014 Wiley Periodicals，Inc.
PurposeTo test the hypothesis that both coronary anatomy and ventricular function can be assessed simultaneously using a single four-dimensional (4D) acquisition.MethodsA free-running 4D whole-heart self-navigated acquisition incorporating a golden angle radial trajectory was implemented and tested in vivo in nine healthy adult human subjects. Coronary magnetic resonance angiography (MRA) datasets with retrospective selection of acquisition window width and position were extracted and quantitatively compared with baseline self-navigated electrocardiography (ECG) -triggered coronary MRA. From the 4D datasets, the left-ventricular end-systolic, end-diastolic volumes (ESV & EDV) and ejection fraction (EF) were computed and compared with values obtained from conventional 2D cine images.ResultsThe 4D datasets enabled dynamic assessment of the whole heart with isotropic spatial resolution of 1.15 mm(3). Coronary artery image quality was very similar to that of the ECG-triggered baseline scan despite some SNR penalty. A good agreement between 4D and 2D cine imaging was found for EDV, ESV, and EF.ConclusionThe hypothesis that both coronary anatomy and ventricular function can be assessed simultaneously in vivo has been tested positive. Retrospective and flexible acquisition window selection allows to best visualize each coronary segment at its individual time point of quiescence. Magn Reson Med 74:1306-1316, 2015. (c) 2014 Wiley Periodicals, Inc.