Factors associated with methadone treatment among injection drug users in Bangkok, Thailand

Factors associated with methadone treatment among injection drug users in Bangkok, Thailand
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DOI:
10.1016/j.jsat.2011.10.022
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发表时间:
2012-07-01
影响因子:
3.9
通讯作者:
Kerr, Thomas
Kerr, Thomas
中科院分区:
医学2区
文献类型:
--
作者:
Fairbairn, Nadia;Hayashi, Kanna;Kerr, Thomas

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人们对注射毒品的特征知之甚少:泰国接受美沙酮治疗的吸毒者(IDU)。我们调查了泰国曼谷社区招募的IDU样本中美沙酮治疗的流行率和相关性。在273名参与者中,143人(52.4%)报告在过去6个月内接受过美沙酮治疗。高龄(调整优势比[AOR]=1.90,95%可信区间[CI]=1.10~3.30)和每周注射咪达唑仑以上(AOR=1.85,95%CI=1.04~3.29)与美沙酮治疗呈正相关,而饮酒(AOR=0.34,95%CI=0.18~0.63)和未注射甲基苯丙胺(AOR=0.49,95%CI=0.29~0.85)与美沙酮治疗呈负相关。在亚分析中,98.6%的吸毒者继续注射美沙酮,最常见的停止注射美沙酮的原因是被监禁(49%)。应实施以美沙酮维持疗法为形式的循证成瘾治疗,并注意在这种情况下同时注射咪达唑仑。(C)2012 Elsevier Inc.保留所有权利。
Little is known about the characteristics of injection drug :users (IDU) who take methadone treatment in Thailand. We examined prevalence and correlates of methadone treatment among a community-recruited sample of IDU in Bangkok, Thailand. Among 273 participants, 143 (52.4%) reported accessing methadone treatment within the previous 6 months. Older age (adjusted odds ratio [AOR] = 1.90, 95% confidence interval [Cl] = 1.10-3.30) and more than weekly midazolam injection (AOR = 1.85, 95% Cl = 1.04-3.29) were positively associated, whereas alcohol use (AOR = 0.34, 95% Cl = 0.18-0.63) and noninjection methamphetamine use (AOR = 0.49, 95% Cl = 0.29-0.85) were negatively associated with methadone treatment. In subanalyses, 98.6% of IDU on methadone continued to inject drugs, and the most common reason for stopping methadone was becoming incarcerated (49%). Evidence-based addiction treatment in the form of methadone maintenance therapy, with attention paid to concomitant midazolam injection in this setting, should be implemented. (C) 2012 Elsevier Inc. All rights reserved.