Bradycardia and Cardiac Arrest Caused by Intramyometrial Injection of Vasopressin During a Laparoscopically Assisted Myomectomy
Bradycardia and Cardiac Arrest Caused by Intramyometrial Injection of Vasopressin During a Laparoscopically Assisted Myomectomy
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DOI：
10.1097/aog.0b013e318187e795
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发表时间：
2009-02-01
影响因子：
7.2
通讯作者：
Tsutsumi, Osamu
中科院分区：
文献类型：
--
作者：
Hobo, Rutsuko;Netsu, Sachiko;Tsutsumi, Osamu
背景：加压素常用于局部以减少手术中的失血量。使用低浓度（小于0.05-0.3单位/mL）的加压素局部浸润被认为是安全的。使用低剂量的加压素是不是没有副作用，它有时也会导致致命的并发症。案例：在一个健康的妇女与多个子宫肌瘤，我们经历了一个心脏骤停的情况下，子宫肌内注射加压素后立即在总剂量为11个单位（0.2单位/毫升）。结论：小剂量加压素局部浸润子宫肌层可引起致命的心肺并发症。
BACKGROUND: Vasopressin is often used locally to reduce blood loss during surgery. The use of a local infiltration of a low concentration of vasopressin, less than 0.05-0.3 units/mL, has been considered to be safe. The use of low-dose vasopressin is not free of side effects, and it can also sometimes cause lethal complications.CASE: In a healthy woman with multiple uterine myomas, we experienced a case of sudden cardiac arrest immediately after the intramyometrial injection of vasopressin at a total dose of 11 units (0.2 units/mL). The patient was successfully resuscitated.CONCLUSION: Local intramyometrial infiltration of low-dose vasopressin may cause lethal cardiopulmonary complications.