DOPAMINERGIC-NEURONS IN NEMATODE CAENORHABDITIS-ELEGANS
DOPAMINERGIC-NEURONS IN NEMATODE CAENORHABDITIS-ELEGANS
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DOI：
10.1002/cne.901630207
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发表时间：
1975-01-01
影响因子：
2.5
通讯作者：
BRENNER, S
中科院分区：
文献类型：
--
作者：
SULSTON, J;DEW, M;BRENNER, S
多巴胺是线虫线虫两性形态中八个神经元的推定递质。这些神经元包括被认为是机械感觉的头和头神经元。雄鸟的尾巴上还有另外六个多巴胺能神经元。已筛选出甲醛诱导荧光缺陷且不同程度缺乏多巴胺的突变体，但对触摸不敏感。比较了优雅蛔虫的多巴胺能神经元和蛔虫的同源神经元。
Dopamine is the putative transmitter of eight neurons in the hermaphrodite form of the nematodeCaenorhabditis elegans. These include the cephalic and deirid neurons, which are believed to be mechanosensory. The male has an additional six dopaminergic neurons in the tail. Mutants have been selected which have defects in the formaldehyde induced fluorescence and lack dopamine to varying degrees, but they are not insensitive to touch. The dopaminergic neurons of C.elegansare compared with the homologous neurons inAscaris lumbricoides.