Developing a database of published reports of randomised clinical trials in pain research
Developing a database of published reports of randomised clinical trials in pain research
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DOI：
10.1016/0304-3959(96)03033-3
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发表时间：
1996-08-01
期刊：
影响因子：
7.4
通讯作者：
McQuay, H
中科院分区：
文献类型：
--
作者：
Jadad, AR;Carroll, D;McQuay, H
在广泛的文献检索后，创建了1950年至1990年出版的疼痛研究随机临床试验（RCT）数据库。通过应用1966年至1990年的MEDLINE检索策略，并通过手工检索1950年至1990年期间出版的40种生物医学期刊的100多万页，确定了8000多项RCT。这些随机对照试验发表在800多种期刊上，其中85%以上发表于1976年至1990年之间。如果过去15年的趋势持续下去，到2000年，总共将有超过15000篇关于疼痛缓解的RCT发表。详细描述了在疼痛缓解和其他领域的信息的识别、检索和管理过程中确保有效利用资源的方法。重点是完善MEDLINE检索策略的重要性，对使用志愿者手工检索期刊和仔细监测的过程中的每一个步骤。数据库的潜在用途，以指导临床和研究决策进行了讨论。
A database of randomised clinical trials (RCTs) in pain research published from 1950 to 1990 was created following an extensive literature search. By applying a refined MEDLINE search strategy from 1966 to 1990 and by hand-searching more than 1 000 000 pages of a total of 40 biomedical journals published during the period 1950-1990, more than 8000 RCTs were identified. The RCTs were published in more than 800 journals and over 85% appeared between 1976 and 1990. If the trend of the last 15 years persists, a total of more than 15 000 RCTs will be published in pain relief by the year 2000. A detailed description of methods to ensure efficient use of resources during the identification, retrieval and management of the information in pain relief and other fields is given. Emphasis is made on the importance of refining MEDLINE search strategies, on the use of volunteers to hand-search journals and on careful monitoring of each of the steps of the process. The potential uses of the database to guide clinical and research decisions are discussed.