RELATION BETWEEN GROWTH AND REPLICATION IN BACTERIA
RELATION BETWEEN GROWTH AND REPLICATION IN BACTERIA
复制标题
DOI：
10.1016/0022-5193(79)90051-1
复制
发表时间：
1979-01-01
影响因子：
2
通讯作者：
YOUNG, R
中科院分区：
文献类型：
--
作者：
BREMER, H;CHURCHWARD, G;YOUNG, R
细菌中染色体复制的控制取决于细胞的生长;当每个复制起点的细胞质量（或蛋白质）达到一定的临界水平时，一轮复制开始。该起始质量的相对值先前通过评价涉及放射性标记细菌培养物的年龄分级的实验来估计。一个理论分析，允许一个简单而准确的方法来确定这个起始质量从几个参数容易观察到的指数文化，而不需要年龄分馏。
The control of chromosome replication in bacteria depends on the cell growth; a round of replication is initiated when the cell mass (or protein) per replication origin has reached a certain critical level. Relative values of this initiation mass were previously estimated from the evaluation of experiments involving age fractionation of radioactively labeled bacterial cultures. A theoretical analysis is presented which permits a simple and accurate method to determine this initiation mass from a few parameters easily observable with exponential cultures, without the need for age fractionation.