High altitude reduces infection rate of COVID-19 but not case-fatality rate
High altitude reduces infection rate of COVID-19 but not case-fatality rate
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DOI：
10.1016/j.resp.2020.103494
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发表时间：
2020-10-01
影响因子：
2.3
通讯作者：
Gonzales, Gustavo F.
中科院分区：
文献类型：
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作者：
Segovia-Juarez, Jose;Castagnetto, Jesus M.;Gonzales, Gustavo F.
冠状病毒病19（COVID-19）是由严重急性呼吸道综合征冠状病毒2（SARS-CoV-2）引起的大流行病。这表明，高海拔生活可能会降低COVID-19感染率和病死率（病例/死亡）。我们研究了秘鲁COVID-19大流行的数据，该大流行于2020年3月6日记录了首例病例。截至2020年6月13日，有6498人死亡，224，132人为SARS-CoV-2阳性。使用来自海拔3米至4342米的185个省会城市的数据，我们证实了先前的报告，即高海拔地区的COVID-19感染减少。然而，病死率与海拔高度无关。我们还首次提出证据表明，女性对COVID-19死亡的保护随着居住海拔的增加而减少。
Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID-19 infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was recorded on March 6th, 2020. By June 13, 2020 there were 6498 deaths, and 224,132 SARS-CoV-2 positives. Using data from 185 capitals of provinces with altitudes ranging from 3 to 4342 m, we confirm previous reports that infection with COVID-19 at high altitude is reduced. However, case-fatality rate is not dependent of altitude. We have also presented first evidence that female protection towards death by COVID-19 is reduced as altitude of residence increases.