Insights into amyloid fibril formation from mass spectrometry
Insights into amyloid fibril formation from mass spectrometry
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DOI：
10.2174/092986606775338416
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发表时间：
2006-01-01
影响因子：
1.6
通讯作者：
Robinson, CV
中科院分区：
文献类型：
--
作者：
Caddy, GL;Robinson, CV
质谱在淀粉样蛋白研究中变得越来越重要，特别是在纤维形成和表征的机制中。在这篇综述中，我们强调关键的实验，提供证据的不同构象，相互作用和展开中间体的蛋白质与淀粉样疾病。
Mass spectrometry has become increasingly important in amyloid research specifically in the mechanism of formation and characterization of fibrils. In this review we highlight key experiments that provide evidence for different conformations, interactions and unfolding intermediates in proteins associated with amyloid diseases.