SOME CONSEQUENCES OF CAPILLARY-PERMEABILITY TO MACROMOLECULES - STARLINGS HYPOTHESIS RECONSIDERED
SOME CONSEQUENCES OF CAPILLARY-PERMEABILITY TO MACROMOLECULES - STARLINGS HYPOTHESIS RECONSIDERED
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DOI：
10.1152/ajpheart.1986.250.5.h706
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发表时间：
1986-05-01
影响因子：
--
通讯作者：
RENKIN, EM
中科院分区：
文献类型：
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作者：
RENKIN, EM
斯塔林的假说将毛细管壁上的液体运动归因于流体静力和胶体渗透力的相互作用。90年来，它一直被认为是血浆到间质液体平衡的基础。它最初的陈述是基于毛细血管对血浆蛋白的不渗透性的概念。然而，随着血浆蛋白质跨毛细管交换知识的发展，它的配方逐渐被修改，以允许蛋白质运输以及蛋白质运输与容量流动的相互作用。在本讲座的正文中，我们回顾了斯塔林假说的概念演变的最重要方面。
Starling's hypothesis ascribes fluid movements across capillary walls to the interaction of hydrostatic and colloid osmotic forces. For 90 years it has been recognized as the basis of plasma-to-interstitial fluid balance. Its original statement was based on the notion of capillary impermeability to plasma proteins. However, as knowledge of transcapillary exchange of plasma proteins developed, its formulation was progressively modified to allow for protein transport and for interaction of protein transport with volume flow. The most important aspects of the conceptual evolution of Starling's hypothesis are reviewed in the text of this lecture.