ChIP and ChIP-Related Techniques: Expanding the Fields of Application and Improving ChIP Performance.
ChIP and ChIP-Related Techniques: Expanding the Fields of Application and Improving ChIP Performance.
复制标题
ChIP 和 ChIP 相关技术：扩大应用领域并提高 ChIP 性能。
作者：
N. Visa;A. Jordán
体内蛋白质-DNA相互作用可以通过染色质免疫沉淀（ChIP）来检测和定量。ChIP有助于表观遗传学的发展，并为许多ChIP相关技术的发展奠定了基础，这些技术提供了有关基因组组织和功能的宝贵信息。在这里，我们提供了一个介绍ChIP和讨论ChIP在不同的研究领域的应用。我们还审查了一些已设计的策略，以提高ChIP的性能。
Protein-DNA interactions in vivo can be detected and quantified by chromatin immunoprecipitation (ChIP). ChIP has been instrumental for the advancement of epigenetics and has set the groundwork for the development of a number of ChIP-related techniques that have provided valuable information about the organization and function of genomes. Here, we provide an introduction to ChIP and discuss the applications of ChIP in different research areas. We also review some of the strategies that have been devised to improve ChIP performance.
影响因子：
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作者：
D. Stewart;A. Tomita;Yunbo Shi;J. Wong
通讯作者：
D. Stewart;A. Tomita;Yunbo Shi;J. Wong
DOI：
10.1073/pnas.81.14.4275
发表时间：
1984-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
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作者：
GILMOUR, DS;LIS, JT
通讯作者：
LIS, JT