Efficient visible light photocatalysis of [2+2] enone cycloadditions
Efficient visible light photocatalysis of [2+2] enone cycloadditions
复制标题
DOI：
10.1021/ja805387f
复制
发表时间：
2008-10-01
影响因子：
15
通讯作者：
Yoon, Tehshik P.
中科院分区：
文献类型：
--
作者：
Ischay, Michael A.;Anzovino, Mary E.;Yoon, Tehshik P.
本文报道了Ru（bipy）（3）Cl（2）作为可见光催化剂催化[2+2]烯酮环加成反应。各种芳基烯酮容易参与反应，并且在环丁烷产物的形成中的非对映选择性优异。我们提出了一种机制，其中光生Ru（bipy）（3）（+）配合物促进单电子还原的烯酮基板，随后进行自由基阴离子环加成。该方法的效率非常高，可以使用入射阳光作为唯一的照射源进行快速，高产率的[2+2]环化。
We report that Ru(bipy)(3)Cl(2) can serve as a visible light photocatalyst for [2+2] enone cycloadditions. A variety of aryl enones participate readily in the reaction, and the diastereoselectivity in the formation of the cyclobutane products is excellent. We propose a mechanism in which a photogenerated Ru(bipy)(3)(+) complex promotes one-electron reduction of the enone substrate, which undergoes subsequent radical anion cycloaddition. The efficiency of this process is extremely high, which allows rapid, high-yielding [2+2] cyclizations to be conducted using incident sunlight as the only source of irradiation.