Misinterpretation of Hereditary Breast Cancer Risk and Its Association with Information Sharing Motives among Women at Low Likelihood of Carrying a BRCA1/2 Mutation.
Misinterpretation of Hereditary Breast Cancer Risk and Its Association with Information Sharing Motives among Women at Low Likelihood of Carrying a BRCA1/2 Mutation.
复制标题
对携带 BRCA1/2 突变可能性较低的女性的遗传性乳腺癌风险及其与信息共享动机的关联的误解。
DOI：
10.1159/000511131
复制
发表时间：
2020
影响因子：
1.7
通讯作者：
Guan,Yue
中科院分区：
文献类型：
--
作者：
Zhao,Jingsong;McBride,ColleenM;Guan,Yue
在这份简短的报告中，我们询问女性基于携带BRCA 1/2突变的低可能性对乳腺癌风险的解释是否与她们的信息共享行为有关，以及误解是否与分享结果的动机有关。方法在乳房X光检查诊所完成简短家族史评估并被认为携带BRCA 1/结果1/3（44/148）的女性与社交网络中的人分享了她们的家族史筛查结果。结果：信息分享主要是与一级女性亲属表达的救济的感觉（77%，33/43）。基于乳腺癌风险解释的共享可能性没有差异。然而，妇女谁误解了一般乳腺癌风险的结果的影响，报告更多的动机，以分享他们的社会网络比那些谁准确地解释了他们的乳腺癌risk.ConclusionsAs家族史为基础的遗传性乳腺癌筛查广泛实施的结果，大多数妇女谁是不太可能携带BRCA 1/2突变的沟通需要必须考虑。误解这一结果对乳腺癌风险的影响的女性的动机表明，误解可能会传播到更广泛的家庭网络。
PurposeIn this brief report, we ask whether women’s interpretation of breast cancer risk based on their low likelihood of carrying a BRCA1/2 mutation is associated with their information-sharing behavior, and whether misinterpretation is associated with motives for sharing the result.MethodsWomen in mammography clinics who completed a brief family history assessment and deemed to be at low likelihood of carrying a BRCA1/2 mutation were asked to complete a 1-time online survey between June 2016 and January 2017.ResultsOne-third (44/148) of women shared their family history screen result with someone in their social network. Result information was shared largely with a first-degree female relative to express feelings of relief (77%, 33/43). There were no differences in likelihood of sharing based on breast cancer risk interpretation. However, women who misinterpreted the implications of the result for general breast cancer risk reported more motives to share the result with their social network than those who accurately interpreted their breast cancer risk.ConclusionsAs family history-based screening for hereditary breast cancer is broadly implemented, the communication needs of the majority of women who will be unlikely of carrying a BRCA1/2 mutation must be considered. The motives of women who misinterpreted the implications of this result for breast cancer risk suggest the possibility that miscommunication could be spread to the broader family network.