Replication of hemorrhagic fever viruses in monocytic cells.

Replication of hemorrhagic fever viruses in monocytic cells.
复制标题

出血热病毒在单核细胞中的复制。

DOI:
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复制
发表时间:
1989
期刊:
Reviews of Infectious Diseases
影响因子:
--
通讯作者:
T. Cosgriff
T. Cosgriff
中科院分区:
--
文献类型:
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作者:
R. Lewis;J. Morrill;P. Jahrling;T. Cosgriff

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相似文献

单核细胞在抵御许多病毒方面发挥着核心作用。在某些感染中,它们是病毒复制的靶细胞。越来越多的证据表明,这些细胞在止血调节中也可能是重要的。单核细胞在病毒性出血热出血发病机制中所起的作用目前还不确定。单核细胞和单核细胞系已被用于研究病毒在体外感染这些细胞的能力。几个因素可能影响特定病毒感染单核细胞的能力,包括病毒的特异性抗血清和细胞成熟程度。细胞成熟对裂谷热病毒在U937细胞系中复制的影响进行了讨论,根据其他病毒对单核细胞的感染性的研究。提供了支持特异性抗体增强皮钦德病毒和拉沙热病毒对U937细胞的感染性的能力的数据。
Monocytes play a central role in protection against many viruses. In some infections they are target cells for viral replication. There is increasing evidence that these cells may also be important in regulation of hemostasis. The part played by monocytic cells in the pathogenesis of hemorrhage in the viral hemorrhagic fevers is presently uncertain. Monocytes and monocytic cell lines have been used to investigate the ability of viruses to infect these cells in vitro. Several factors may affect the ability of a particular virus to infect monocytic cells, including specific antiserum to virus and the degree of cellular maturation. The effect of cellular maturation on the replication of Rift Valley fever virus in the U937 cell line is discussed in light of studies on the infectivity of other viruses for monocytic cells. Data supporting the ability of specific antibody to enhance the infectivity of Pichinde virus and Lassa fever virus for U937 cells are presented.
在与 T 淋巴细胞条件培养基孵育期间调节人单核细胞系 U937 的表面抗原:检测 T4 抗原及其在正常血液单核细胞上的存在。
DOI: --
发表时间: 1983
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Moscicki,RA;Amento,EP;Krane,SM;Kurnick,JT;Colvin,RB
通讯作者: Colvin,RB
外周血单核细胞呼吸道病毒感染:与细胞衰老和体外干扰素产生的相关性。
DOI: 10.1099/0022-1317-68-6-1749
发表时间: 1987
期刊: The Journal of general virology
影响因子: --
作者:
Krilov,LR;Hendry,RM;Godfrey,E;McIntosh,K
通讯作者: McIntosh,K