Reconstruction Magnetic Resonance Neurography in Chronic Inflammatory Demyelinating Polyneuropathy
Reconstruction Magnetic Resonance Neurography in Chronic Inflammatory Demyelinating Polyneuropathy
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DOI：
10.1002/ana.24314
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发表时间：
2015-02-01
影响因子：
11.2
通讯作者：
Kuwabara, Satoshi
中科院分区：
文献类型：
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作者：
Shibuya, Kazumoto;Sugiyama, Atsuhiko;Kuwabara, Satoshi
为了研究慢性炎症性脱髓鞘性多神经病变（CIDP）神经肥大的分布和模式，对33例患者进行了短tau反转恢复图像三维重建的磁共振神经成像。这项技术清楚地显示了从颈根到近臂神经干的纵向形态学变化。88%的患者神经扩张。从临床亚型来看，典型的CIDP患者表现为对称性、根性肥大，而Lewis-Sumner综合征患者表现为神经干多灶梭状肥大。神经肥大的模式可能反映了每一种CIDP亚型不同的病理生理。Ann Neurol 2014。
To study distribution and patterns of nerve hypertrophy in chronic inflammatory demyelinating polyneuropathy (CIDP), magnetic resonance neurography with 3-dimensional reconstruction of short tau inversion recovery images was performed in 33 patients. This technique clearly showed longitudinal morphological changes from the cervical roots to the nerve trunks in the proximal arm. Nerve enlargement was detected in 88% of the patients. According to the clinical subtype of CIDP, typical CIDP patients showed symmetric and root-dominant hypertrophy, whereas Lewis-Sumner syndrome patients had multifocal fusiform hypertrophy in the nerve trunks. The patterns of nerve hypertrophy presumably reflect the different pathophysiology of each CIDP subtype. Ann Neurol 2014.