PATHOLOGICAL CHANGES IN TEMPORAL ARTERIES REMOVED FROM UNSELECTED CADAVERS
PATHOLOGICAL CHANGES IN TEMPORAL ARTERIES REMOVED FROM UNSELECTED CADAVERS
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DOI：
10.1136/jcp.14.2.115
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发表时间：
1961-01-01
影响因子：
3.4
通讯作者：
GRESHAM, GA
中科院分区：
文献类型：
--
作者：
AINSWORTH, R;BALMFORTH, GV;GRESHAM, GA
描述了老化的颞动脉的进行性退行性改变。这些改变在老年患者中通常是严重的，因此他们在诊断性活组织检查中的存在并不能证明过去或现在有颞动脉炎。在随机检查的一系列尸检中，有两名患者的颞动脉出现了与过去已知患有颞动脉炎的患者相同的变化；在这两例患者中，除了巨细胞性大动脉炎之外，还有一种巨细胞性大动脉炎。在单个活检标本中区分治愈的动脉炎和因年龄而引起的退行性改变可能很困难。此外，类固醇治疗可能会阻止疾病的进展，从而不会发生大体内膜增厚和动脉壁血管形成。巨细胞性动脉炎并不罕见。在39例60岁以上患者的随机尸检中发现了两例。
Progressive degenerative changes in ageing temporal arteries are described. These changes are usually severe in elderly patients, hence their presence in diagnostic biopsies provides no evidence of temporal arteritis past or present. In two patients in the series of random necropsies examined there were changes in the temporal arteries identical with those seen in patients known to have suffered from temporal arteritis in the past; in both these cases there was, in addition a giant cell aortitis. The distinction between healed arteritis and degenerative changes due to age in a single biopsy specimen may be difficult. Furthermore, it is possible that steroid treatment may arrest the progess of the disease so that gross intimal thickening and vascularization of the artery wall do not occur. Giant cell arteritis is not a rare disease. Two examples were discovered in 39 random necropsies on patients over 60 years of age.