High-throughput mass spectrometry: the mechanism of sudan azo dye fragmentation by ESI tandem mass spectrometry and extensive deuterium labeling experiments.
High-throughput mass spectrometry: the mechanism of sudan azo dye fragmentation by ESI tandem mass spectrometry and extensive deuterium labeling experiments.
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DOI：
10.1002/jms.1236
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发表时间：
2007-08
期刊：
影响因子：
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通讯作者：
L. Di Donna;A. De Nino;L. Maiuolo;F. Mazzotti;A. Napoli;R. Salerno;G. Sindona
中科院分区：
文献类型：
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作者：
L. Di Donna;A. De Nino;L. Maiuolo;F. Mazzotti;A. Napoli;R. Salerno;G. Sindona
用质谱法研究偶氮化合物的气相化学可以追溯到这个特殊的研究领域被引入物理有机化学工具库的时候。从质子化前体的偶氮双键的断裂的机制进行了讨论，参考氘标记的参考化合物的行为。所研究的分子属于苏丹家族，其结果可用于通过同位素稀释法检测不同基质中的这些潜在致癌化合物。
The investigation of the gas-phase chemistry of azo compounds by mass spectrometry dates back to the introduction of this peculiar research field into the armory of physical organic chemistry tools. The mechanism of the fragmentation of the azo double bond from the protonated precursor is discussed with reference to the behavior of deuterium-labeled reference compounds. The investigated molecules belong to the sudan family and the results can be used for the detection of these potential carcinogenic compounds in different matrices by means of the isotope dilution method.