RELATIONSHIP BETWEEN ENDOGENOUS SERUM INSULIN CONCENTRATION AND GLUCOSE UPTAKE IN FOREARM MUSCLES OF NONDIABETICS
RELATIONSHIP BETWEEN ENDOGENOUS SERUM INSULIN CONCENTRATION AND GLUCOSE UPTAKE IN FOREARM MUSCLES OF NONDIABETICS
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DOI：
10.1172/jci105818
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发表时间：
1968-01-01
影响因子：
15.9
通讯作者：
ORSKOV, H
中科院分区：
文献类型：
--
作者：
CHRISTENSEN, NJ;ORSKOV, H
在人体前臂上进行的一系列实验(旨在研究免疫测定的内源性血清胰岛素水平和血糖浓度的变化对肌肉葡萄糖摄取的影响)获得了以下结果：肌肉葡萄糖摄取与同时动脉血清胰岛素浓度之间存在高度显著的相关性；高血糖时葡萄糖摄取与同时动脉血糖浓度之间没有相关性；在动脉血清胰岛素浓度约为220[mU]U/ml时，胰岛素对肌肉葡萄糖摄取的影响最大。然而，这一观察仅基于少数几个实验。
In a series of experiments on the human forearm (preparation designed to examine the effects of variations in immunologically determined endogenous serum insulin levels and of blood glucose concentrations on muscular glucose uptake) the following results were obtained: a highly significant correlation between muscular glucose uptake and simultaneous arterial serum insulin concentration; no correlation between glucose uptake and simultaneous arterial blood glucose concentration during hyperglycemia; a maximal insulin effect on muscular glucose uptake at arterial serum insulin concentrations at about 220 [mu]U/ml. This observation is, however, based on only a few experiments.