Studies on Indonesian Medicinal Plants. VII. Alkaloids of Arcangelisia flava
Studies on Indonesian Medicinal Plants. VII. Alkaloids of Arcangelisia flava
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印度尼西亚药用植物研究。
DOI：
10.1021/np50023a011
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发表时间：
1982
影响因子：
5.1
通讯作者：
A. Svendsen
中科院分区：
文献类型：
--
作者：
R. Verpoorte;J. Siwon;G. V. Essen;M.E.M. tieken;A. Svendsen
从大白芷的茎和根中分离得到了六种季生物碱，分别是沙利芬定、脱氢堇黄碱、黄根碱、罂粟碱、小檗碱和棕榈碱，以及三种叔生物碱，羟基小檗碱、马马碱和同芳香碱。Arcangelisia属与Coscinium属和Anamirta属一起属于menispermacae的Coscieae族。大白花属包括两种（Forman, 1）。A. flava （L.）梅尔是一种产于东南亚的藤本植物。鼓室足类；&舒姆。)Diels是迄今为止只在新几内亚发现的藤本植物。这两个物种是由果实的大小来区分的，后者的果实比前者大。黄酮类植物的多种药用用途已被报道：作为退烧药、滋补品、消炎药、祛痰药和止血药，以及治疗肝炎和消化不良(Santos (2), van Steenis (3), Kondo (4)， Estrada等人（5),Quisumbing(6)）。Wells(7)报道了黄芪茎中含有小檗碱。Santos(2)鉴定出小檗碱、黄麻根碱和柱状碱，并分离出一种生物碱，称为“shobakunine”。后来证明这是棕榈碱和小檗碱的混合物(8)。Garcia等人(9)在a . loureirii Diels （a . flava的同义词）的茎中检测到小檗碱、棕榈碱和黄毒根碱，在根中检测到小檗碱和黄毒根碱。
From stem and roots of Arcangelisia flava six quaternary alkaloids, thalifendine, dehydrocorydalmine, jatrorrhizine, pycnarrhine, berberine and palmatine and three tertiary alkaloids, hydroxy-berberine, limacine and homoaromoline, have been isolated and identified by their spectral data.The genus Arcangelisia belongs, together with the genera Coscinium and Anamirta, to the tribe Coscieae of the Menispermaceae. The genus Arcangelisia comprises two species (Forman, 1). A. flava (L.) Merr is a liana found in South-East Asia. A. tympanopoda (Lauberb. & K. Schum.) Diels is a liana found so far only in New-Guinea. The two species are differentiated by the size of the fruits, the latter one having larger fruits thanthe former. Various medicinal uses of A. flava havebeen reported: as a febrifuge, tonic, abortive, expectorant and emmanogogue and against hepatitis and indigestion (Santos (2), van Steenis (3), Kondo (4), Estrada el al.(5), Quisumbing (6)). Wells (7) reported the presence of berberine in the stem of A. flava. Santos (2) identified berberine, jatrorrhizine and columbamine and isolated an alkaloid which was called “shobakunine”. This was later shown to be a mixture of palmatine and berberine (8). Garcia et al.(9) detected berberine, palmatine and jatrorrhizine inthe stem and berberine and jatrorrhizine in the roots of A. loureirii Diels (a synonym for A. flava (1)).