First isolation of Burkholderia tropica from a neonatal patient successfully treated with imipenem

First isolation of Burkholderia tropica from a neonatal patient successfully treated with imipenem
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DOI:
10.1016/j.ijid.2009.03.005
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发表时间:
2010-01-01
影响因子:
8.4
通讯作者:
Ravichandran, Manicham
Ravichandran, Manicham
中科院分区:
医学2区
文献类型:
--
作者:
Deris, Zakuan Zainy;Van Rostenberghe, Hans;Ravichandran, Manicham

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我们报告了第一例人类热带伯克霍尔德杆菌感染病例。该患者是一名早产儿,患有坏死性小肠结肠炎并伴有肠穿孔,需要手术干预。造口护理和喂养困难是一个长期存在的问题。大约 4 个月大时,他因热带伯氏杆菌而患上败血症。连续三次血培养培养出了这种生物体。经过亚胺培南疗程和术后肠梗阻消退后,该微生物从血液中清除。我们的案例表明,环境和植物病原体可能导致人类感染,尤其是在免疫功能低下的情况下。 (C) 2009 年国际传染病学会。由爱思唯尔有限公司出版。保留所有权利。
We report the first case of a human Burkholderia tropica infection. The patient was a premature neonate who had necrotizing enterocolitis with bowel perforation requiring surgical intervention. The stoma care and difficulties in feeding were a chronic problem. At the age of almost 4 months he developed septicemia due to B. tropica. Three consecutive blood cultures grew this organism. The organism was cleared from the blood after a course of imipenem and resolution of post-operative ileus. Our case suggests that environmental and plant pathogens can cause human infection especially in those in an immunocompromised condition. (C) 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.