UPR signaling at the nexus of plant viral, bacterial, and fungal defenses
UPR signaling at the nexus of plant viral, bacterial, and fungal defenses
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植物病毒、细菌和真菌防御系统中的UPR信号
DOI：
10.1016/j.coviro.2020.11.001
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发表时间：
2021-04-01
影响因子：
5.9
通讯作者：
Pajerowska-Mukhtar, Karolina M.
中科院分区：
文献类型：
--
作者：
Verchot, Jeanmarie;Pajerowska-Mukhtar, Karolina M.
近年来，我们对植物内质网胁迫反应与病毒感染以及细菌和真菌疾病相关的认识取得了重大进展。在植物中，病毒感染引起的内质网胁迫包括几种信号通路，其中包括未折叠蛋白反应（UPR），促进伴侣蛋白的表达，以实现适当的蛋白质折叠。了解内质网应激信号的各个方面如何广泛参与病原体反应，以及那些特定于病毒感染的方面，对于区分可能与病毒感染性和疾病特异性相关的广泛细胞防御和过程所必需的特征非常重要。
In recent years there have been significant advances in our understanding of the ER stress responses in plants that are associated with virus infection, as well as bacterial and fungal diseases. In plants, ER stress induced by virus infection includes several signaling pathways that include the unfolded protein response (UPR) to promote the expression of chaperone proteins for proper protein folding. Understanding how facets of ER stress signaling broadly engage in pathogen responses, as well as those that are specific to virus infection is important to distinguishing features essential for broad cellular defenses and processes that may be specifically linked to viral infectivity and disease.