A randomized trial of a prenatal genetic testing interactive computerized information aid.

A randomized trial of a prenatal genetic testing interactive computerized information aid.
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DOI:
10.1002/pd.4347
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发表时间:
2014-06
期刊:
影响因子:
3
通讯作者:
Grobman, William A.
Grobman, William A.
中科院分区:
医学2区
文献类型:
--
作者:
Yee, Lynn M.;Wolf, Michael;Mullen, Rebecca;Bergeron, Ashley R.;Bailey, Stacy Cooper;Levine, Robert;Grobman, William A.

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确定交互式计算机程序是否可以提高患者关于遗传筛查和诊断概念的知识。在这项随机试验中,妊娠6-26周的女性被分配接受标准护理,并接受基于提供者的咨询,或接受通过交互式计算机程序进行的增强咨询。基于计算机的工具传达了有关基因检测选项的信息。妇女在接触后立即和2-4周进行23项内容知识测试。使用T检验比较两组在这两个点的测试分数。150名女性被随机分为两组。各组在人口统计学特征方面相似。随机分配到交互式工具的女性在即时问卷中正确回答问题的比例显著高于接受标准咨询的女性(69.4% ±14.2% vs. 46.0% ± 15.2%,p<0.001)。123名(82%)参与者参加了后续测试。随机分配到该工具的女性继续正确回答问题的比例显著更高(60.6% ± 16% vs. 49.7% ± 18.9%,p=.001)。教育、健康素养、电子健康素养和与提供者的其他讨论与教育干预的差异性益处无关。病人导向的交互式计算机程序可以帮助提供者传达有关遗传筛查和诊断概念的相关信息。
To determine whether an interactive computer program could improve patient knowledge regarding genetic screening and diagnostic concepts. In this randomized trial, women 6–26 weeks’ gestation were assigned to standard care with provider-based counseling or to augmented counseling with an interactive computer program. The computer-based tool conveyed information about genetic testing options. Women were administered a 23-item test of content knowledge immediately and 2–4 weeks after exposure. Test scores were compared between groups at both points using T-tests. 150 women were randomized equally between groups. Groups were similar with regard to demographic characteristics. Women randomized to the interactive tool correctly answered a significantly greater proportion of questions than those who received standard counseling (69.4% ±14.2% vs. 46.0% ± 15.2%, p<.001) on the immediate questionnaire. One hundred and twenty-three (82%) participants participated in the follow-up test. Women randomized to the tool continued to correctly answer a significantly greater proportion of questions (60.6% ± 16% vs. 49.7% ± 18.9%, p=.001). Education, health literacy, electronic health literacy, and other discussions with providers were not associated with a differential benefit from the educational intervention. A patient-directed interactive computer program may help providers to convey relevant information about genetic screening and diagnostic concepts.
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