Erroneous Arrhenius: modified arrhenius model best explains the temperature dependence of ectotherm fitness.
Erroneous Arrhenius: modified arrhenius model best explains the temperature dependence of ectotherm fitness.
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DOI：
10.1086/653662
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发表时间：
2010-08
期刊：
影响因子：
--
通讯作者：
Kingsolver JG
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文献类型：
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作者：
Knies JL;Kingsolver JG
随着温度的升高，适合度的最初上升归因于阿累尼乌斯动力学，其中反应速度随着温度的升高而指数增加。基于Arrhenius的模型通常假设在某个生理温度范围内所有限速酶都处于100%活性构象的单一限速反应(S)。我们使用微生物的数据集来测试这一假设，这些微生物在许多温度和广泛的温度范围内都有适合度(内在种群增长率)的测量，以及在较低温度下测量的不同的外胚层动物。当在许多温度下都可以进行测量时，严格的阿累尼乌斯动力学在生理温度范围内是不适用的。然而，在较窄的温度范围内，我们不能严格拒绝阿累尼乌斯动力学。温度范围也影响对适合度的温度依赖性的估计。这些结果表明，阿雷尼乌斯动力学只适用于温度范围较窄的外温带，这使得识别温度依赖的一般模式的尝试变得更加复杂。
The initial rise of fitness that occurs with increasing temperature is attributed to Arrhenius kinetics, in which rates of reaction increase exponentially with increasing temperature. Models based on Arrhenius typically assume single rate-limiting reaction(s) over some physiological temperature range for which all the rate-limiting enzymes are in 100% active conformation. We test this assumption using datasets for microbes that have measurements of fitness (intrinsic rate of population growth) at many temperatures and over a broad temperature range, and for diverse ectotherms that have measurements at fewer temperatures. When measurements are available at many temperatures, strictly Arrhenius kinetics is rejected over the physiological temperature range. However, over a narrower temperature range, we cannot reject strictly Arrhenius kinetics. The temperature range also affects estimates of the temperature dependence of fitness. These results indicate that Arrhenius kinetics only apply over a narrow range of temperatures for ectotherms, complicating attempts to identify general patterns of temperature dependence.