Size-dependant heating rates of iron oxide nanoparticles for magnetic fluid hyperthermia.
Size-dependant heating rates of iron oxide nanoparticles for magnetic fluid hyperthermia.
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DOI：
10.1016/j.jmmm.2008.12.017
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发表时间：
2009-07
影响因子：
2.7
通讯作者：
Krishnan KM
中科院分区：
文献类型：
--
作者：
Gonzales-Weimuller M;Zeisberger M;Krishnan KM
使用有机金属化合物的热分解方法，我们合成了高质量的氧化铁纳米颗粒，其尺寸可调节至~ 15 nm，并通过涂覆生物相容性聚合物将其转移到水相。测量这些颗粒的磁行为，并使用Chantrell方法拟合对数正态分布，证实它们的多分散性非常窄。通过对这些单分散颗粒进行量热测量，我们第一次明确地证明，在给定的频率下，超顺磁性颗粒的加热速率取决于颗粒尺寸，与早期的理论预测一致。
Using the thermal decomposition of organometallics method we have synthesized high-quality, iron oxide nanoparticles of tailorable size up to ~15nm and transferred them to a water phase by coating with a biocompatible polymer. The magnetic behavior of these particles was measured and fit to a log-normal distribution using the Chantrell method and their polydispersity was confirmed to be very narrow. By performing calorimetry measurements with these monodisperse particles we have unambiguously demonstrated, for the first time, that at a given frequency, heating rates of superparamagnetic particles are dependent on particle size, in agreement with earlier theoretical predictions.