Influenza vaccine effectiveness among 50-64-year-old persons during a season of poor antigenic match between vaccine and circulating influenza virus strains: Colorado, United States, 2003-2004

Influenza vaccine effectiveness among 50-64-year-old persons during a season of poor antigenic match between vaccine and circulating influenza virus strains: Colorado, United States, 2003-2004
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DOI:
10.1016/j.vaccine.2006.05.129
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发表时间:
2007-01-02
期刊:
影响因子:
5.5
通讯作者:
Bridges, Carolyn B.
Bridges, Carolyn B.
中科院分区:
医学3区
文献类型:
--
作者:
Herrera, Guillermo A.;Iwane, Marika K.;Bridges, Carolyn B.

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在2003-2004年流感季节,我们对科罗拉多州50-64岁的居民进行了流感疫苗有效性(VE)的病例对照研究。病例(n = 330)从实验室确认的流感报告中确定给科罗拉多州公共卫生和环境部(CDPHE)。对照组(n = 1055)采用随机数字拨号电话调查。在无高危医疗条件者和有高危医疗条件者中,VE分别为60%(43-72%)和48%(21-66%)。无流感相关疾病和有流感相关疾病的人的住院率分别为90%(68-97%)和36%(0-63%)。Elsevier Ltd.出版。
During the 2003-2004 influenza season, we conducted a case-control study of influenza vaccine effectiveness (VE) among Colorado residents aged 50-64 years. Cases (n = 330) were identified from laboratory-confirmed influenza reports to the Colorado Department of Public Health and Environment (CDPHE). Controls (n = 1055) were recruited by random-digit dial telephone survey. VE was 60% (43-72%) and 48% (21-66%) among those without and with high-risk medical conditions, respectively. VE was 90% (68-97%) and 36% (0-63%) against influenza-related hospitalization for persons without and with high-risk conditions, respectively. Published by Elsevier Ltd.