Prevalence of and Racial Differences in Pterygium A Multiethnic Population Study in Asians
Prevalence of and Racial Differences in Pterygium A Multiethnic Population Study in Asians
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DOI：
10.1016/j.ophtha.2012.02.009
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发表时间：
2012-08-01
期刊：
影响因子：
13.7
通讯作者：
Wong, Tien Yin
中科院分区：
文献类型：
--
作者：
Ang, Marcus;Li, Xiang;Wong, Tien Yin
目的：描述翼状胬肉在多种族亚洲人群中的患病率和危险因素，并检查种族差异。设计：在位于赤道以北1度的新加坡进行的基于人群的研究。参与者：数据来自2004年至2011年进行的3项基于人群的研究的8906名参与者，研究对象为40岁及以上的马来人、印度人和中国人。由经过培训的眼科医生进行标准化裂隙灯检查，以检查眼前节是否存在翼状胬肉。每个受试者都进行了标准化的全身和眼部检查，访谈者管理的问卷调查，并进行血液检查以评估风险因素。结果：翼状胬肉的总患病率为10.1%（n = 900），其中1.6%（n = 142）为重度翼状胬肉。任何翼状胬肉的患病率在马来人中（15.5%）比中国人（7.0%; P
Purpose: To describe the prevalence and risk factors of pterygium in a multiethnic Asian population and to examine racial differences.Design: Population-based study in Singapore, located 1 degrees north of the equator.Participants: Data were analyzed from 8906 participants from 3 population-based studies of Malays, Indians, and Chinese persons 40 years of age and older conducted between 2004 and 2011.Methods: Standardized slit-lamp examinations were performed by trained study ophthalmologists to examine the anterior segment for evidence of pterygium. Every subject underwent standardized systemic and ocular examinations, interviewer-administered questionnaires, and blood investigations for risk factor assessment. Regression and principle component analysis models were constructed to study the relationship of race and other factors to pterygium.Main Outcome Measures: Any pterygium and severe (grade 3 or opaque) pterygium.Results: The overall prevalence of any pterygium was 10.1% (n = 900), of which severe pterygium was seen in 1.6% (n = 142). The prevalence of any pterygium was more common in Malays (15.5%) than Chinese (7.0%; P