Impact of Direct Soil Exposures from Airborne Dust and Geophagy on Human Health

Impact of Direct Soil Exposures from Airborne Dust and Geophagy on Human Health
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空气中的灰尘和食土直接暴露土壤对人类健康的影响

DOI:
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发表时间:
2010
影响因子:
--
通讯作者:
C. Sing
C. Sing
中科院分区:
综合性期刊3区
文献类型:
--
作者:
David B. Sing;C. Sing

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随着进化时间的推移,人类与土壤之间形成了一种复杂的生物关系。在这里,我们描述土壤暴露的模式及其生物学意义。我们考虑了两种类型的土壤暴露,第一种是持续暴露在空气中,第二种是饮食摄入土壤,或食地。可以假定,空气中的粉尘和土壤的摄入影响了特定DNA序列的进化,这些DNA序列控制着生物系统,使单个有机体能够利用、适应和/或防止暴露在土壤材料中。我们回顾了土壤暴露作为表观遗传信号的环境来源的可能性,这些表观遗传信号可能影响我们的基因组在决定健康和疾病方面的功能。
Over evolutionary time humans have developed a complex biological relationship with soils. Here we describe modes of soil exposure and their biological implications. We consider two types of soil exposure, the first being the continuous exposure to airborne soil, and the second being dietary ingestion of soils, or geophagy. It may be assumed that airborne dust and ingestion of soil have influenced the evolution of particular DNA sequences which control biological systems that enable individual organisms to take advantage of, adapt to and/or protect against exposures to soil materials. We review the potential for soil exposure as an environmental source of epigenetic signals which may influence the function of our genome in determining health and disease.
基因组与环境暴露之间的动态关系是人类常见疾病的原因。
DOI: 10.1159/000081252
发表时间: 2004
影响因子: --
作者:
Sing,CharlesF;Stengard,JariH;Kardia,SharonLR
通讯作者: Kardia,SharonLR
DOI: 10.1016/j.nut.2003.09.011
发表时间: 2004-01-01
期刊: NUTRITION
影响因子: 4.4
作者:
Waterland, RA;Jirtle, RL
通讯作者: Jirtle, RL