Noninvasive Swansea criteria are valuable alternatives for diagnosing acute fatty liver of pregnancy in a Chinese population
Noninvasive Swansea criteria are valuable alternatives for diagnosing acute fatty liver of pregnancy in a Chinese population
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DOI：
10.1080/14767058.2016.1269316
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发表时间：
2017-01-01
影响因子：
1.8
通讯作者：
Wang, Xie-Tong
中科院分区：
文献类型：
--
作者：
Wang, Shan;Li, Shan-Ling;Wang, Xie-Tong
背景资料：本研究旨在评估Swansea标准在诊断中国人群妊娠急性脂肪肝（AFLP）中的诊断和预后价值。所有选定的情况下，重新评估使用斯旺西标准，特别关注的非侵入性标准，因为进行肝活检，这一适应症是罕见的在中国population.Results：百分之九十点四的患者符合五个或更多的斯旺西标准。31例阳性的6个或更多的斯旺西标准，但有患者之间没有显着差异时，使用截止标准6。当患者少于7项标准时，死产、连续性血液净化（CBP）治疗、子宫切除术和产后出血的频率不会增加。然而，7项或7项以上标准阳性的患者死产风险显著较高，CBP治疗率也较高（p
Background: This study aims to assess the diagnostic and prognostic value of Swansea criteria in diagnosing acute fatty liver of pregnancy (AFLP) in a Chinese population.Methods: A retrospective study was conducted on 52 Chinese women diagnosed with AFLP. All selected cases were reassessed using the Swansea criteria with special focus on the noninvasive criteria, since performing a liver biopsy for this indication is rare in a Chinese population.Results: Ninety point four percent of patients fulfilled five or more of the Swansea criteria. Thirty-one cases were positive for six or more Swansea criteria, but there were no significance differences between patients when using a cutoff criteria 6. When patients were positive for less than seven criteria, frequency of stillbirth, continuous blood purification (CBP) treatment, hysterectomy, and postpartum hemorrhage were not increased. However, patients who were positive for seven or more criteria had a significantly higher risk of stillbirth and a higher rate of CBP treatment (p