Atrial septostomy: stationary angioplasty balloon technique--experimental work and preliminary clinical applications.
Atrial septostomy: stationary angioplasty balloon technique--experimental work and preliminary clinical applications.
复制标题
房间隔造口术：固定血管成形球囊技术——实验工作和初步临床应用。
DOI：
10.1007/bf00796998
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发表时间：
1994
影响因子：
1.6
通讯作者：
Kan,J
中科院分区：
文献类型：
--
作者：
Mitchell,SE;Anderson,JH;Swindle,MM;Strandberg,JD;Kan,J
本文提出了一种利用固定直径血管成形术球囊建立心房间通信的新方法。固定式球囊鼻中隔造口术通过封闭的房间隔在19头猪和18只新生羔羊中使用经鼻中隔技术通过未闭的卵圆孔建立心房通讯。在鼻中隔完好的动物中，使用直径大于12mm的球囊，心房交通持续通畅。房通的平均直径为血管成形术球囊扩张直径的96%。对于孔未闭的新生羔羊，在4周时观察到平滑的卵圆形心房通讯，使用直径大于15mm的球囊可保持开放。开口的平均直径为所用血管成形术球囊直径的81%。这种新方法在5个病人身上得到了成功的应用。5例患者临床症状均得到缓解。总之，静止血管成形术球囊房间隔造口术在房间隔完整的动物和卵圆孔未闭的动物中都能有效地产生房间通信，并保持4-14周通畅。
A new approach to creating an interatrial communication using a stationary fixeddiameter angioplasty balloon is presented.Stationary balloon septostomy was used to create an atrial communication in 19 young swine using a transseptal technique through a closed atrial septum, and in 18 newborn lambs through a patent foramen ovale.In animals with an intact septum, there was persistent patency of the atrial communication using balloons larger than 12 mm in diameter. The average diameter of the atrial communication was 96% of the expanded diameter of the angioplasty balloon. For newborn lambs with a patent foramen, a smooth oval atrial communication was noted by 4 weeks, and there was persistent patency of the opening using balloons larger than 15 mm in diameter. The average diameter of the opening was 81% of the diameter of the angioplasty balloon used.The new procedure was used successfully in five patients. All five showed resolution of the clinical symptomology.In conclusion, stationary angioplasty balloon atrial septostomy has been effective in producing interatrial communications, which remained patent for 4–14 weeks, in animals with intact septum, as well as in those with a patent foramen ovale.