The reasoning behind decisions not to take up antiretroviral therapy in Australians infected with HIV
The reasoning behind decisions not to take up antiretroviral therapy in Australians infected with HIV
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DOI：
10.1258/0956462001916065
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发表时间：
2000-06-01
影响因子：
1.4
通讯作者：
Batrouney, CG
中科院分区：
文献类型：
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作者：
Gold, RS;Hinchy, J;Batrouney, CG
少数感染艾滋病毒的澳大利亚人没有服用抗逆转录病毒药物。这项研究调查了他们决定不这样做的原因。任何感染艾滋病毒但未服用抗逆转录病毒药物的人都可以参加。采用自我管理的匿名问卷，主要招募方法是通过在悉尼和墨尔本的同性恋社区报纸上插入问卷。所有应答者都被问及人口统计、以前的艾滋病定义疾病、t细胞和病毒载量监测以及以前使用抗逆转录病毒药物等问题。此外，曾考虑接受抗逆转录病毒治疗，但后来决定不这样做的答复者，得到了一份其决定的可能原因清单，并要求说明每种原因在其想法中所起的作用。在270名受访者中，绝大多数是男同性恋者。八分之一的人经历过艾滋病定义疾病。三分之二的人最近做了t细胞和病毒载量测试。三分之一的人以前服用过抗逆转录病毒药物。超过三分之二的人考虑过抗逆转录病毒治疗，其中大多数人对这个问题进行了相当多的思考。在HIV疾病的不同阶段，不接受治疗的原因没有太大差异。最常见的个人原因是害怕副作用。从对原因数据的因素分析中得出的重要主题包括：对传统医学治疗方法的不信任、与服用抗逆转录病毒药物有关的实际问题、接受治疗会引起的不愉快的想法以及对死亡的接受。这些发现可以被医生和咨询师用来帮助患者澄清和评估他们对抗逆转录病毒治疗的担忧。
A substantial minority of HIV-infected Australians are not taking antiretroviral drugs. This study investigated the reasons behind their decision not to do so. Anyone who was HIV-infected but not taking antiretroviral drugs could participate. A self-administered, anonymous questionnaire was used, the principal recruitment method being through insertion of the questionnaire into gay community newspapers in Sydney and Melbourne. All respondents were asked questions covering demographics, previous AIDS-defining illnesses, T-cell and viral load monitoring, and previous use of antiretroviral drugs. In addition, respondents who had considered going on antiretroviral treatment, but then decided not to do so, were given a list of possible reasons for their decision and asked to indicate how much each played a role in their thinking. Of the 270 respondents, the great majority were gay men. One-eighth had experienced AIDS-defining illnesses. Two-thirds had recently had T-cell and viral load tests. One-third had taken antiretroviral drugs previously. Over two-thirds had considered antiretroviral therapy, most having given the matter quite some thought. Reasons for not taking up therapy did not differ greatly at different stages of HIV disease. The most common individual reason was fear of side effects. important themes that emerged from factor analysis of the reasons data included distrust of conventional medical approaches to treatment, practical problems associated with taking antiretroviral drugs, unpleasant thoughts that being on therapy would evoke, and acceptance of the idea of dying. The findings can be used by doctors and counsellors to help patients clarify and evaluate their concerns about antiretroviral therapy.