Correlating Gray Matter Volume with Individual Difference in the Flanker Interference Effect.
Correlating Gray Matter Volume with Individual Difference in the Flanker Interference Effect.
复制标题
将灰质体积与侧翼干扰效应中的个体差异相关联
DOI：
10.1371/journal.pone.0136877
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Abbasi Nu
中科院分区：
文献类型：
--
作者：
Chen C;Yang J;Lai J;Li H;Yuan J;Abbasi Nu
Eriksen侧翼任务已被广泛用于测量认知控制，但到目前为止，关于这一任务中的神经解剖学特性如何与表现相关的信息仍然很少。利用基于体素的形态测量技术(VBM)，本研究确定了一组灰质体积(GM)与受试者干扰抑制效率正相关的分布区域。这些区域包括双侧额前回、左侧脑岛、左侧颞下回、左侧顶下小叶。使用一种新的机器学习算法和平衡交叉验证程序进一步分析证实，在这些区域，GM行为关联不太可能是离群值的副产品，相反，灰质体积可以可靠地预测参与者的干扰抑制效率。这些结果从神经解剖学的角度强调了额顶叶和脑岛系统对干扰抑制的脑功能的重要性。
The Eriksen Flanker task has been widely used as a measurement of cognitive control, however till now information is still scarce about how the neuroanatomical properties are related to performance in this task. Using voxel-based morphometry technique (VBM), the current study identified a set of distributed areas where the gray matter volume (GM) correlated positively with participants’ efficiency in interference inhibition. These areas included the bilateral prefrontal gyri, left insula and inferior temporal gyrus, the left inferior parietal lobule. Further analysis using a novel machine learning algorithm with balanced cross-validation procedure confirmed that in these areas the GM-behavioral association was unlikely a byproduct of outlier values, instead, the gray matter volume could predict reliably participants’ interference inhibition efficiency. These results underscore the importance of the fronto-parietal and insula systems to the brain functioning of interference inhibition from the neuroanatomical perspective.