Osteoarthritis of the knee after injury to the anterior cruciate ligament or meniscus: The influence of time and age
Osteoarthritis of the knee after injury to the anterior cruciate ligament or meniscus: The influence of time and age
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DOI：
10.1016/s1063-4584(05)80017-2
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发表时间：
1995-12-01
影响因子：
7
通讯作者：
Lohmander, LS
中科院分区：
文献类型：
--
作者：
Roos, H;Adalberth, T;Lohmander, LS
一项回顾性横断面研究对 1012 名在膝关节损伤后不同时间出现膝关节不适的患者进行了回顾性横断面研究，通过关节镜和放射学检查评估了软骨变化的程度。患者按照年龄、性别、创伤日期和损伤类型进行分类。根据关节镜检查和负重射线照片的结果，软骨状况按 1-10 等级分级。前十字韧带损伤（孤立或合并半月板或副韧带损伤）的患者首次出现骨关节炎（OA）放射学症状（关节间隙狭窄）的平均年龄约为 40 岁，而孤立的半月板损伤的患者平均年龄约为 50 岁，具有相同的疾病阶段。两个研究组平均在受伤后约 10 年首次出现 OA 放射学体征，并且随着受伤和检查之间时间的增加，关节镜和关节损伤的放射学体征越来越严重。对于17岁至30岁之间遭受孤立性半月板损伤的患者，出现OA放射学症状的平均时间约为15年，而对于30岁以上发生相同损伤的患者，相应的时间间隔仅为约5年。我们由此得出结论，随着关节损伤和检查之间时间的增加，膝关节骨关节炎变得越来越严重。膝关节损伤的老年患者比年轻人更早出现骨关节炎变化。
The degree of cartilage changes by arthroscopic and radiologic examination was evaluated in a retrospective, cross-sectional study of 1012 patients with knee complaints at different times after knee injury. Patients were classified by age, sex, trauma date and type of injury. The condition of the cartilage was graded on a 1-10 scale based on findings at arthroscopy and on weight-bearing radiographs. Patients with injury to the anterior cruciate ligament (isolated or combined with injury to meniscus or collateral ligaments) showed the first radiologic signs (joint space narrowing) of osteoarthritis (OA) at an average age of about 40 years, while patients with isolated meniscus injury had the same stage of disease at an average age of about 50 years. Both study groups displayed the first radiologic signs of OA on average about 10 years after the injury and showed increasingly serious arthroscopic and radiologic signs of joint damage with increased time between injury and examination. For patients who sustained an isolated meniscus injury between the ages of 17 and 30, the average time until development of radiologic signs of OA was about 15 years, while for those who had the same injury over the age of 30, the corresponding time interval was only about 5 years. We conclude from this that knee OA becomes increasingly severe with increased time between joint injury and examination. OA changes appear sooner in older patients with knee injury than in the young.