Sequence-dependent fluorescence of DNA-hosted silver nanoclusters
Sequence-dependent fluorescence of DNA-hosted silver nanoclusters
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DOI：
10.1002/adma.200702380
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发表时间：
2008-01-18
影响因子：
29.4
通讯作者：
Fygenson, Deborah Kuchnir
中科院分区：
文献类型：
--
作者：
Gwinn, Elisabeth G.;O'Neill, Patrick;Fygenson, Deborah Kuchnir
DNA结合的银纳米发射体位于宿主DNA的单链区域中。它们的荧光对DNA碱基序列及其二级结构都很敏感。使用标准落射荧光技术可检测到来自由DNA“发夹”（其适合于掺入DNA支架中）托管的单个发射体的荧光。
DNA-bound silver nanoemitters reside in single-stranded regions of the host DNA. Their fluorescence is sensitive to both the DNA base sequence and its secondary structure. Fluorescence from individual emitters hosted by DNA "hairpins", which are suitable for incorporation into DNA scaffolds, is detectable using standard epifluorescence techniques.