Effects of Annual Mass Treatment with Ivermectin for Onchocerciasis on the Prevalence of Intestinal Helminths
Effects of Annual Mass Treatment with Ivermectin for Onchocerciasis on the Prevalence of Intestinal Helminths
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DOI：
10.4269/ajtmh.2010.10-0033
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发表时间：
2010-09-01
影响因子：
3.3
通讯作者：
Richards, Frank O., Jr.
中科院分区：
文献类型：
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作者：
Gutman, Julie;Emukah, Emmanuel;Richards, Frank O., Jr.
我们评估了每年分发伊维菌素（IV）治疗盘尾丝虫病对学龄（SAC）和学龄前（PAC）土壤传播蠕虫（STH）感染率的影响。通过比较接受治疗13年的村庄的儿童与未治疗地区社会经济相似村庄的儿童，我们为Kato Katz检查使用了1.031 SAC和211 PAC。蛔虫患病率较低（SAC 3%对12%）。P < 0 0 0 0 1，PAC 3%对10%，P < 0 0 5 1）和鞭虫（SAC 6%对10%，P = 0 0 12，PAC 1%对8%，P = 0 0 19）。而钩虫感染率则无显著性差异（SAC 38%vs42%，P = 0.20; PAC 21%vs27%，P = 0.30）。治疗区鞭虫感染率低于WHO规定的大规模驱虫阈值，而钩虫感染率低于WHO规定的大规模驱虫阈值。
We evaluated the effect of annual ivermectin (IV) distribution for onchocerciasis on the prevalence of soil transmitted helminth (STH) infections in school-aged (SAC) and preschool-aged (PAC) children by comparing children in villages that had received treatment for 13 years to those from socioeconomically similar villages in untreated areas We em oiled 1.031 SAC and 211 PAC for Kato Katz examinations Treated areas had a lower prevalence of Ascaris (SAC 3% versus 12%. P < 0 0001, PAC 3% versus 10%, P < 0 051) and Trichuris (SAC 6% versus 10%, P = 0 012, PAC 1% versus 8%, P = 0019). but not hookworm (SAC 38% versus 42%, P = 0 20, PAC 21% versus 27%, P = 0.30) The prevalence of A scarfs or Trichuris in treated areas was below the WHO threshold for mass antihelminthic treatment (MDA), hut not for hookworm We conclude that benzimidazole MDA in IV treatment areas is indicated to effectively control hookworm