The Impact of Comorbid Depressive and Anxiety Disorders on Severity of Anorexia Nervosa in Adolescent Girls
The Impact of Comorbid Depressive and Anxiety Disorders on Severity of Anorexia Nervosa in Adolescent Girls
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DOI：
10.1097/nmd.0000000000000194
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发表时间：
2014-10-01
影响因子：
1.9
通讯作者：
Fennig, Silvana
中科院分区：
文献类型：
--
作者：
Brand-Gothelf, Ayelet;Leor, Shani;Fennig, Silvana
我们研究了抑郁症和焦虑症共病对青春期女孩神经性厌食症（AN）严重程度的影响。将患有AN的青春期女孩（N = 88）分为一组和另一组无共病疾病，并比较两组之间疾病严重程度的主观和客观指标。共病组的所有四个分量表和进食障碍检查总分以及所有进食障碍量表-2分量表的得分均显著高于非共病组，但贪食症除外。与非共病组相比，共病组也有更多的自杀企图和住院治疗。有史以来最低的体重指数，AN症状的持续时间和AN发病年龄没有显着的组间差异。我们的研究结果表明，AN与共病抑郁症和焦虑症是一个更严重的临床变异的障碍，特别是在严重程度的心理症状和自杀风险。
We examined the impact of comorbid depression and anxiety disorders on the severity of anorexia nervosa (AN) in adolescent girls. Adolescent girls with AN (N = 88) were divided into one group with and another group without comorbid disorders, and selected subjective and objective measures of illness severity were compared between the two groups. The comorbid group had significantly higher scores than the noncomorbid group for all four subscales and total scores of the Eating Disorders Examination as well as for all Eating Disorders Inventory-2 subscales, except for bulimia. The comorbid group also had significantly more suicide attempts and hospitalizations compared with the noncomorbid group. There were no significant group differences for the lowest ever body mass index, duration of AN symptoms, and age at AN onset. Our findings suggest that AN with comorbid depression and anxiety disorder is a more severe clinical variant of the disorder, especially with respect to severity of psychological symptoms and suicide risk.